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Article

Screening genetic variability at the CNR1 gene in both major depression etiology and clinical response to citalopram treatment.

Psychopharmacology - 1 Jun 2013

Mitjans Marina, Serretti Alessandro, Fabbri Chiara, Gastó Cristóbal, Catalán Rosa, Fañanás Lourdes, Arias Bárbara

Abstract excerpt

RATIONALE: The endocannabinoid system has been implicated in the pathogenesis of major depression (MD) as well as in the mediation of antidepressant drug effects. OBJECTIVES: To analyze CNR1 gene variants in MD and clinical response to citalopram (selective serotonin re-uptake inhibitors [SSRI]). METHODS: The role of CNR1 gene (rs806368, rs1049353, rs806371, rs806377 and rs1535255) was investigated in 319...

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Identifiers

PMID: 23407780
DOI: 10.1007/s00213-013-2995-y

Genes

CNR1

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