Pre-miR146a expression in follicular carcinomas of the thyroid.

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Article

Pre-miR146a expression in follicular carcinomas of the thyroid.

Pathologica - 1 Jun 2014

Roncati L, Pignatti E, Vighi E, Magnani E, Kara E, Rochira V, Carani C, Simoni M, Maiorana A

Abstract excerpt

INTRODUCTION: Micro-RNA, a new class of small, non-coding RNAs, have been shown to be deregulated in several human carcinomas. In particular, SNP rs2910164 in pre-miR146a appears to be correlated with papillary thyroid carcinoma and may be involved in its genetic predisposition. Since data on follicular thyroid carcinomas (FTC) are lacking, we evaluated the involvement of SNP rs2910164 in FTC. METHODS:...

Topics

Adenocarcinoma, Follicular
Adolescent
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
Female
Gene Expression Regulation, Neoplastic
Gene Frequency
Genetic Predisposition to Disease
Humans
Male
MicroRNAs
Middle Aged
Phenotype
Polymorphism, Single Nucleotide
RNA Precursors
Real-Time Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 25291868

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