Article
Association between the rs2910164 polymorphism in pre-Mir-146a sequence and thyroid carcinogenesis.
PloS one - 1 Jan 2013
Wei Wen-Jun, Wang Yu-Long, Li Duan-Shu, Wang Yu, Wang Xiao-Feng, Zhu Yong-Xue, Yang Ya-Jun, Wang Zhuo-Ying, Ma Yan-Yun, Wu Yi, Jin Li, Ji Qing-Hai, Wang Jiu-Cun
Abstract excerpt
BACKGROUND: Rs2910164, a Single nucleotide polymorphism (SNP) located in the precursor microRNA sequence of miR-146a, is the only MicroRNA sequence SNP studied in papillary thyroid cancer (PTC). Association studies had been performed in US and UK-Northern European populations, but results were inconsistence. This study evaluated the association between rs2910164 and the risk of PTC as well as benign thyroid tumor...
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