Article
The rs2910164 Genetic Variant of miR-146a-3p Is Associated with Increased Overall Mortality in Patients with Follicular Variant Papillary Thyroid Carcinoma.
International journal of molecular sciences - 26 Feb 2018
Kotlarek Marta, Kubiak Anna, Czetwertyńska Małgorzata, Świerniak Michał, Gierlikowski Wojciech, Kolanowska Monika, Bakuła-Zalewska Elwira, Jhiang Sissy M, Jażdżewski Krystian, Wójcicka Anna
Abstract excerpt
Aberrant expression of the sodium-iodide symporter (NIS) and the resistance to post-operative radioactive iodide treatment is a crucial cause of higher mortality of some thyroid cancer patients. In this study, we analyzed the impact of miR-146a on the expression and function of NIS and on the overall survival of thyroid cancer patients. The study included 2441 patients (2163 women; 278 men); including 359 cases...
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