Article
Association of the miR-149 Rs2292832 polymorphism with papillary thyroid cancer risk and clinicopathologic characteristics in a Chinese population.
International journal of molecular sciences - 14 Nov 2014
Wei Wen-Jun, Lu Zhong-Wu, Li Duan-Shu, Wang Yu, Zhu Yong-Xue, Wang Zhuo-Ying, Wu Yi, Wang Yu-Long, Ji Qing-Hai
Abstract excerpt
(1) BACKGROUND: The genetic predisposition to papillary thyroid cancer (PTC) is far from clearly elucidated. Rs2292832 is a genetic polymorphism that located in the precursor of mir-149 and has been studied in diverse cancers. Thus far, the role of rs2292832 in PTC tumorigenesis and progression was unclear; (2) METHOD: Rs2292832 was genotyped in 838 PTCs, 495 patients with thyroid benign tumors (BNs) and 1006...
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