Article
The common genetic variant rs944289 on chromosome 14q13.3 associates with risk of both malignant and benign thyroid tumors in the Japanese population.
Thyroid : official journal of the American Thyroid Association - 1 Mar 2015
Rogounovitch Tatiana I, Bychkov Andrey, Takahashi Meiko, Mitsutake Norisato, Nakashima Masahiro, Nikitski Alyaksandr V, Hayashi Tomayoshi, Hirokawa Mitsuyoshi, Ishigaki Katsu, Shigematsu Kazuto, Bogdanova Tetiana, Matsuse Michiko, Nishihara Eijun, Minami Shigeki, Yamanouchi Kosho, Ito Masahiro, Kawaguchi Takahisa, Kondo Hisayoshi, Takamura Noboru, Ito Yasuhiro, Miyauchi Akira, Matsuda Fumihiko, Yamashita Shunichi, Saenko Vladimir A
Abstract excerpt
BACKGROUND: Several single nucleotide polymorphisms (SNP) have been identified to be associated with the risk for differentiated thyroid cancer in populations of distinct ethnic background. The relationship of these genetic markers to a benign tumor of the thyroid, follicular adenoma (FA), is not well established. METHODS: In a multicenter retrospective case-control study, five thyroid cancer-related...
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