Down-regulation of microRNAs controlling tumourigenic factors in follicular thyroid carcinoma.

doi:10.1530/JME-11-0039

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Article

Down-regulation of microRNAs controlling tumourigenic factors in follicular thyroid carcinoma.

Journal of molecular endocrinology - 1 Feb 2012

Rossing Maria, Borup Rehannah, Henao Ricardo, Winther Ole, Vikesaa Jonas, Niazi Omid, Godballe Christian, Krogdahl Annelise, Glud Martin, Hjort-Sørensen Christian, Kiss Katalin, Bennedbæk Finn Noe, Nielsen Finn Cilius

Abstract excerpt

The molecular determinants of thyroid follicular nodules are incompletely understood and assessment of malignancy is a diagnostic challenge. Since microRNA (miRNA) analyses could provide new leads to malignant progression, we characterised the global miRNA expression in follicular adenoma (FA) and follicular carcinoma (FC). Comparison of carcinoma and adenoma with normal thyroid revealed 150 and 107...

Topics

Adenocarcinoma, Follicular
Adult
Aged
Cell Line, Tumor
Cell Proliferation
Cell Transformation, Neoplastic
Cluster Analysis
Computational Biology
Down-Regulation
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression Profiling

Gene Expression Regulation, Neoplastic

Humans

Male

MicroRNAs

Middle Aged

Mutation

Prognosis

Source

Open in PubMed

Identifiers

PMID: 22049245
DOI: 10.1530/JME-11-0039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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