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Article

Kinetics of cellobiohydrolase (Cel7A) variants with lowered substrate affinity.

The Journal of biological chemistry - 21 Nov 2014

Kari Jeppe, Olsen Johan, Borch Kim, Cruys-Bagger Nicolaj, Jensen Kenneth, Westh Peter

Abstract excerpt

Cellobiohydrolases are exo-active glycosyl hydrolases that processively convert cellulose to soluble sugars, typically cellobiose. They effectively break down crystalline cellulose and make up a major component in industrial enzyme mixtures used for deconstruction of lignocellulosic biomass. Identification of the rate-limiting step for cellobiohydrolases remains controversial, and recent reports have alternately...

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Identifiers

PMID: 25271162
DOI: 10.1074/jbc.M114.604264
PMCID: PMC4239601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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