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Article

Virtual Screening and Discovery of Novel Aurora Kinase Inhibitors

1 Oct 2014

Abstract excerpt

Cancer remains one of the major contributors to human mortality and a hazard to human growth. The search for a new treatment continues unabated. Aurora kinases play an important role in cell cycle, and thus a potential target for the treatment of cancer. In the present work, we aim to discover potential leads against aurora kinase using various rational methods of drug discovery. The available crystal complexes...

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PMID: 25262798
DOI: 10.2174/1568026614666140929151140

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