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Article

Small molecule aurora kinases inhibitors.

Current medicinal chemistry - 1 Jan 2009

Garuti Laura, Roberti Marinella, Bottegoni Giovanni

Abstract excerpt

Aurora kinases represent one of the emerging targets in oncology drug discovery. These kinases play important role in centrosome maturation, chromosome separation and cytokinesis. They are overexpressed in a broad range of tumor cell lines and human primary tumors; thus, their inhibition may open up new opportunities to develop novel anti-cancer agents. A range of potent small molecule inhibitors of Aurora...

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PMID: 19519375
DOI: 10.2174/092986709788682227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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