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Article

Tbx protein level critical for clock-mediated somite positioning is regulated through interaction between Tbx and Ripply.

PloS one - 1 Jan 2014

Wanglar Chimwar, Takahashi Jun, Yabe Taijiro, Takada Shinji

Abstract excerpt

Somitogenesis in vertebrates is a complex and dynamic process involving many sequences of events generated from the segmentation clock. Previous studies with mouse embryos revealed that the presumptive somite boundary is periodically created at the anterior border of the expression domain of Tbx6 protein. Ripply1 and Ripply2 are required for the determination of the Tbx6 protein border, but the mechanism by which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25259583
DOI: 10.1371/journal.pone.0107928
PMCID: PMC4178057

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