Article
Multiple signaling pathways control Tbx6 expression during Xenopus myogenesis.
Acta biochimica et biophysica Sinica - 1 Jun 2004
Fang Pan-Feng, Hu Rui-Ying, He Xing-Yue, Ding Xiao-Yan
Abstract excerpt
Tbx6 is critical for somite specification and myogenesis initiation. It has been shown that Activin/Nodal, VegT/Nodal, FGF, and BMP signaling pathways are involved early in specifying mesoderm or later in patterning mesoderm, and Xnot plays roles in setting up the boundary between notochord and paraxial mesoderm. In this study, we introduce the dominant negative form of above genes into embryos to evaluate if...
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