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Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance

9 Sept 2014

Abstract excerpt

The proteins Foxa1 and Foxa2 belong to the forkhead family of transcription factors and are involved in the development of several tissues, including liver, pancreas, lung, prostate, and the neural system. Both Foxa1 and Foxa2 are also crucial for the specification and differentiation of dopamine (DA) neurons during embryonic development, while about 30% of mice with an embryonic deletion of a single allele of...

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PMID: 25249938
DOI: 10.3389/fncel.2014.00275

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