Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alteration of the Dopamine Receptors' Expression in the Cerebellum of the Lysosomal Acid Phosphatase 2 Mutant (Naked-Ataxia (NAX)) Mouse.

International journal of molecular sciences - 21 Apr 2020

Mehdizadeh Mehdi, Ashtari Niloufar, Jiao Xiaodan, Rahimi Balaei Maryam, Marzban Asghar, Qiyami-Hour Farshid, Kong Jiming, Ghavami Saeid, Marzban Hassan

Abstract excerpt

A spontaneous mutation in the lysosomal acid phosphatase (Acp2) enzyme (nax: naked-ataxia) in experimental mice results in delayed hair appearance and severe cytoarchitectural impairments of the cerebellum, such as a Purkinje cell (PC) migration defect. In our previous investigation, our team showed that Acp2 expression plans a significant role in cerebellar development. On the other hand, the dopaminergic system...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acid Phosphatase
Share to Autophagy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cerebellum

Share to Gene Expression

Share to Immunohistochemistry

Share to Purkinje Cells

Share to Receptors, Dopamine

Source

Open in PubMed Open full text

Identifiers

PMID: 32326360
DOI: 10.3390/ijms21082914
PMCID: PMC7215910

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alteration of the Dopamine Receptors' Expression in the Cerebellum of the Lysosomal Acid Phosphatase 2 Mutant (Naked-Ataxia (NAX)) Mouse.PMID 32326360Read ↗

Reduced Granule Cell Proliferation and Molecular Dysregulation in the Cerebellum of Lysosomal Acid Phosphatase 2 (ACP2) Mutant Mice.Semantic proximity Read ↗

Dopamine receptor and transporter levels are altered in the brain of Purkinje Cell Degeneration mutant mice.Semantic proximity Read ↗

LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased BrainSemantic proximity Read ↗

A new mouse allele of glutamate receptor delta 2 with cerebellar atrophy and progressive ataxia.Semantic proximity Read ↗

Compromised striatal structure and function in mouse models of RARB-related disorderSemantic proximity Read ↗

The Lurcher mouse: fresh insights from an old mutant.Semantic proximity Read ↗

Mutation in the gene encoding lysosomal acid phosphatase (Acp2) causes cerebellum and skin malformation in mouse.Semantic proximity Read ↗

DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson’s diseaseSemantic proximity Read ↗

Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenanceSemantic proximity Read ↗

The control of dopamine neuron development, function and survival: insights from transgenic mice and the relevance to human disease.Semantic proximity Read ↗

Generation and validation of a D1 dopamine receptor Flpo knock-in mouseSemantic proximity Read ↗

A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.