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Article

Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 May 2013

Stott Simon R W, Metzakopian Emmanouil, Lin Wei, Kaestner Klaus H, Hen Rene, Ang Siew-Lan

Abstract excerpt

The maintained expression of transcription factors throughout the development of mesodiencephalic dopaminergic (mDA) neurons suggests multiple roles at various stages in development. Two members of the forkhead/winged helix transcription factor family, Foxa1 and Foxa2, have been recently shown to have an important influence in the early development of mDA neurons. Here we present data demonstrating that these...

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Identifiers

PMID: 23637192
DOI: 10.1523/JNEUROSCI.4774-12.2013
PMCID: PMC6618950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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