Article
Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain.
The International journal of developmental biology - 1 Jan 2010
Di Salvio Michela, Di Giovannantonio Luca G, Omodei Daniela, Acampora Dario, Simeone Antonio
Abstract excerpt
Mesencephalic-diencephalic dopaminergic (mdDA) neurons control motor, sensorimotor and motivated behaviour and their degeneration or abnormal functioning is associated with important pathologies, such as Parkinsons disease and psychiatric disorders. Despite great efforts, the molecular basis and the genetic factors differentially controlling identity, survival and vulnerability to neurodegeneration of mdDA...
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