Article
The presence of -308A TNFα is associated with anemia and thrombocytopenia in patients with myelodysplastic syndromes.
Blood cells, molecules & diseases - 15 Dec 2011
Belli Carolina B, Bestach Yesica, Sieza Yamila, Gelemur Marta, Giunta Mario, Flores María G, Watman Nora, Bengió Raquel, Larripa Irene
Abstract excerpt
Myelodysplastic syndromes (MDS) constitute a heterogeneous group of clonal hematological diseases characterized by refractory cytopenia(s). MDS patients show increased levels of tumor necrosis factor alpha (TNFα) which is a multifunctional proinflammatory cytokine. The aim of this work is to examine the presence of -308A/G TNFα variants and to analyze whether it is associated with clinical parameters in a cohort...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
