Article
[Single nucleotide polymorphism of interferon-gamma gene +874 T/A in patients with aplastic anemia].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2008
Chang Hong, Zhang Jia-You, Meng Wen-Tong
Abstract excerpt
The aim of this study was to investigate whether the single nucleotide polymorphism (SNP) of interferon-gamma (IFN-gamma) +874 T/A correlates with aplastic anemia. Amplification refractory mutation system-polymerase chain reaction was used to amplify the polymorphism gene segment of IFN-gamma +874 A/T from 54 aplastic anemia patients and 51 healthy adults. The results showed that the frequency of IFN-gamma +874...
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