Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Extremely elevated international normalized ratio of warfarin in a patient with CYP2C91/3 and thyrotoxicosis.

Journal of Korean medical science - 1 Sept 2014

Lee Ji Eun, Ryu Duck Hyun, Jeong Ho Jung, Kim Jung Hoon, Jun Ji Eun, Kim June Soo, Lee Soo Youn

Abstract excerpt

A 73-yr-old Korean man with permanent atrial fibrillation visited outpatient clinic with severely increased International Normalized Ratio (INR) values after taking a usual starting dosage of warfarin to prevent thromboembolism. We found out later from his blood tests that he had hyperthyroidism at the time of treatment initiation. His genetic analysis showed CYP2C9*1/*3 and VKORC1+1173TT genotypes. We suspect...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticoagulants
Share to Aspirin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atrial Fibrillation

Share to Cytochrome P-450 CYP2C9

Share to Tandem Mass Spectrometry

Share to Thromboembolism

Share to Vitamin K Epoxide Reductases

Share to Warfarin

Source

Open in PubMed Open full text

Identifiers

PMID: 25246753
DOI: 10.3346/jkms.2014.29.9.1317
PMCID: PMC4168188

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Extremely elevated international normalized ratio of warfarin in a patient with CYP2C9*1/*3 and thyrotoxicosis.PMID 25246753Read ↗

Extremely low warfarin dose in patients with genotypes of CYP2C9*3/*3 and VKORC1-1639A/A.Semantic proximity Read ↗

Pharmacogenetic distribution of warfarin and its clinical significance in Korean patients during initial anticoagulation therapy.Semantic proximity Read ↗

Integrated analysis of clinical and genetic factors on the interindividual variation of warfarin anticoagulation efficacy in clinical practice.Semantic proximity Read ↗

Frequency of VKORC1 (C1173T) and CYP2C9 genetic polymorphisms in Egyptians and their influence on warfarin maintenance dose: proposal for a new dosing regimen.Semantic proximity Read ↗

Low dose requirement for warfarin treatment in a patient with CYP2C9*3/*13 genotype.Semantic proximity Read ↗

VKORC1 gene polymorphisms and adverse events in Croatian patients on warfarin therapy.Semantic proximity Read ↗

Gene polymorphisms and the risk of warfarin-induced bleeding complications at therapeutic international normalized ratio (INR).Semantic proximity Read ↗

Pharmacokinetic and pharmacodynamic variation associated with VKORC1 and CYP2C9 polymorphisms in Thai patients taking warfarin.Semantic proximity Read ↗

Integrating genotypes in the SAMe-TT2R2 score for the prediction of anticoagulation control in Chinese patients with atrial fibrillation on warfarin.Semantic proximity Read ↗

Anticoagulant therapy for a patient with recurrent pulmonary embolism and warfarin resistance：a case report and literature reviewSemantic proximity Read ↗

Prevalence of CYP2C9 and VKORC1 mutation in patients with valvular heart disease in northern Thailand.Semantic proximity Read ↗

Determinants of the over-anticoagulation response during warfarin initiation therapy in Asian patients based on population pharmacokinetic-pharmacodynamic analyses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.