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Article

Integrated analysis of clinical and genetic factors on the interindividual variation of warfarin anticoagulation efficacy in clinical practice.

BMC cardiovascular disorders - 31 May 2023

Sun Bao, Ma Siqing, Xiao Feiyan, Luo Jianquan, Liu Mouze, Liu Wenhui, Luo Zhiying

Abstract excerpt

AIM: The anticoagulation effect of warfarin is usually evaluated by percentage of time in therapeutic range (PTTR), which is negatively correlated with the risk of warfarin adverse reactions. This study aimed to explore the effects of genetic and nongenetic factors on anticoagulation efficacy of warfarin during different therapeutic range. METHODS: We conducted an observational retrospective study aiming at...

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Identifiers

PMID: 37254053
DOI: 10.1186/s12872-023-03321-9
PMCID: PMC10230781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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