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Article

Pharmacogenetic distribution of warfarin and its clinical significance in Korean patients during initial anticoagulation therapy.

Journal of thrombosis and thrombolysis - 1 Nov 2011

Kwon Aerin, Jo Sang-Ho, Im Hyoung-June, Jo Yun-A, Park Ji-Young, Kang Hee Jung, Kim Han-Sung, Cho Hyoun Chan, Lee Young Kyung

Abstract excerpt

During warfarin treatment, determining the optimal dose and maintaining the target PT-INR are challenging. Increasing evidence supports the theory that genotypic polymorphisms influence an individual's warfarin dose requirement. In this study, we evaluated allele frequencies and effects of CYP2C9 and VKORC1 on warfarin response during initial anticoagulation therapy in Korean patients. We enrolled patients who...

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Source

Identifiers

PMID: 21713378
DOI: 10.1007/s11239-011-0616-3

Genes

VKORC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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