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Article

Gene polymorphisms and the risk of warfarin-induced bleeding complications at therapeutic international normalized ratio (INR).

Toxicology and applied pharmacology - 15 Oct 2016

Pourgholi Leyla, Goodarzynejad Hamidreza, Mandegary Ali, Ziaee Shayan, Talasaz Azita Hajhosseini, Jalali Arash, Boroumand Mohammadali

Abstract excerpt

BACKGROUND: Bleeding episodes commonly occur in patients on warfarin treatment even in those within therapeutic range of international normalized ratio (INR). The objective of this study was to investigate the effects of the 8 examined polymorphisms on the risk of bleeding complications in a sample of Iranian patients. METHODS: A total of 552 warfarin treated patients who maintained on a target INR level of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27581200
DOI: 10.1016/j.taap.2016.08.026

Genes

NQO1
EPHX1
VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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