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Article

Prevalence of CYP2C9 and VKORC1 mutation in patients with valvular heart disease in northern Thailand.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Dec 2009

Kuanprasert Srun, Dettrairat Sakchai, Palacajornsuk Poonsub, Kunachiwa Warunee, Phrommintikul Arintaya

Abstract excerpt

BACKGROUND: Warfarin has been widely used for the prevention and treatment of thromboembolism. Warfarin therapy depends on interaction between physiological, environmental, and genetic factors. Vitamin K epoxide reductase (VKORC1) and cytochrome P450 2C9 (CYP2C9) enzyme conjointly determine the warfarin maintenance dose. The prevalence of CYP2C9 and VKORC1 variants varies among ethnic groups. The purpose of the...

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Identifiers

PMID: 20043560

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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