Article
PARK16 is associated with PD in the Malaysian population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2016
Gopalai Aroma Agape, Ahmad-Annuar Azlina, Li Hui-Hua, Zhao Yi, Lim Shen-Yang, Tan Ai Huey, Lim Thien Thein, Eow Gaik Bee, Santhi Puvanarajah, Shanthi Viswanathan, Norlinah Mohamed Ibrahim, Aziz Zariah Abdul, Lim Soo Kun, Tan Chong Tin, Tan Eng-King
Abstract excerpt
PARK16 was identified as a risk factor for Parkinson's disease in a Japanese cohort; however, subsequent studies in the other populations including the Chinese, European, Caucasian, and Chilean have shown a protective role instead. To investigate this locus in our Malaysian cohort, 1,144 individuals were screened for five SNPs in the PARK16 locus and logistic regression analysis showed that the A allele of the...
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