Article
Clinical characteristics of PD patients with LRRK2 G2385R and R1628P variants.
Neuroscience letters - 15 Oct 2018
Liang Dongxiao, Shu Li, Pan Hongxu, Xu Qian, Guo Jifeng, Yan Xinxiang, Tang Beisha, Sun Qiying
Abstract excerpt
LRRK2 is the most common genetic cause of PD. G2385R and R1628 P variants are the most common variants of LRRK2 in Chinese populations. Consensus on the clinical features of G2385R and R1628 P related PD has not been reached yet, although it had been widely studied. In our study, genotype analyses were conducted on 721 PD patients of Chinese origin. A total of 62 G2385R carriers, 32 R1628 P carriers and 623...
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