Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Promotion of growth by Coenzyme Q10 is linked to gene expression in C. elegans.

Biochemical and biophysical research communications - 3 Oct 2014

Fischer Alexandra, Niklowitz Petra, Menke Thomas, Döring Frank

Abstract excerpt

Coenzyme Q (CoQ, ubiquinone) is an essential component of the respiratory chain, a cofactor of pyrimidine biosynthesis and acts as an antioxidant in extra mitochondrial membranes. More recently CoQ has been identified as a modulator of apoptosis, inflammation and gene expression. CoQ deficient Caenorhabditis elegans clk-1 mutants show several phenotypes including a delayed postembryonic growth. Using wild type...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Mutation

Share to Ubiquinone

Source

Identifiers

PMID: 25234594
DOI: 10.1016/j.bbrc.2014.09.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Promotion of growth by Coenzyme Q10 is linked to gene expression in C. elegans.PMID 25234594Read ↗

Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans.Semantic proximity Read ↗

C. elegans knockouts in ubiquinone biosynthesis genes result in different phenotypes during larval development.Semantic proximity Read ↗

Molecular genetics of ubiquinone biosynthesis in animals.Semantic proximity Read ↗

Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis.Semantic proximity Read ↗

Coenzyme Q biosynthesis in health and disease.Semantic proximity Read ↗

Restoring de novo coenzyme Q biosynthesis in Caenorhabditis elegans coq-3 mutants yields profound rescue compared to exogenous coenzyme Q supplementation.Semantic proximity Read ↗

Comparison of a coq7 deletion mutant with other respiration-defective mutants in fission yeast.Semantic proximity Read ↗

Coenzyme Q plays opposing roles on bacteria/fungi and viruses in Drosophila innate immunity.Semantic proximity Read ↗

Ubiquinone is necessary for Caenorhabditis elegans development at mitochondrial and non-mitochondrial sites.Semantic proximity Read ↗

Sensitivity of Caenorhabditis elegans clk-1 mutants to ubiquinone side-chain length reveals multiple ubiquinone-dependent processes.Semantic proximity Read ↗

Restoration of the behavioral rates and lifespan in clk-1 mutant nematodes in response to exogenous coenzyme Q(10).Semantic proximity Read ↗

Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.