Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans.

Mechanisms of ageing and development - 1 Mar 2009

Asencio Claudio, Navas Plácido, Cabello Juan, Schnabel Ralf, Cypser James R, Johnson Thomas E, Rodríguez-Aguilera Juan Carlos

Abstract excerpt

Coenzyme Q (Q) regulates aging in Caenorhabditis elegans, and its deficiency leads to a variety of pathologies in humans. We used a coq-8 deleted strain to study the role of Q in C. elegans development and how it influences life span. Endogenous Q(9) content of coq-8(ok840) knockouts was demonstr...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans Proteins
Share to Fertility
Share to Gene Knockout Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gonads

Share to Longevity

Share to Ubiquinone

Share to Uridine

Source

Identifiers

PMID: 19007804
DOI: 10.1016/j.mad.2008.10.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19007804-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans.PMID 19007804Read ↗

Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria.Semantic proximity Read ↗

Reproductive fitness and quinone content of Caenorhabditis elegans clk-1 mutants fed coenzyme Q isoforms of varying length.Semantic proximity Read ↗

Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis.Semantic proximity Read ↗

Restoring de novo coenzyme Q biosynthesis in Caenorhabditis elegans coq-3 mutants yields profound rescue compared to exogenous coenzyme Q supplementation.Semantic proximity Read ↗

C. elegans knockouts in ubiquinone biosynthesis genes result in different phenotypes during larval development.Semantic proximity Read ↗

Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q.Semantic proximity Read ↗

Sensitivity of Caenorhabditis elegans clk-1 mutants to ubiquinone side-chain length reveals multiple ubiquinone-dependent processes.Semantic proximity Read ↗

Ubiquinone is necessary for Caenorhabditis elegans development at mitochondrial and non-mitochondrial sites.Semantic proximity Read ↗

Molecular genetics of ubiquinone biosynthesis in animals.Semantic proximity Read ↗

Promotion of growth by Coenzyme Q10 is linked to gene expression in C. elegans.Semantic proximity Read ↗

Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.Semantic proximity Read ↗

Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.