Article
Comparison of a coq7 deletion mutant with other respiration-defective mutants in fission yeast.
The FEBS journal - 1 Nov 2008
Miki Risa, Saiki Ryoichi, Ozoe Yoshihisa, Kawamukai Makoto
Abstract excerpt
Among the steps in ubiquinone biosynthesis, that catalyzed by the product of the clk-1/coq7 gene has received considerable attention because of its relevance to life span in Caenorhabditis elegans. We analyzed the coq7 ortholog (denoted coq7) in Schizosaccharomyces pombe, to determine whether coq7 has specific roles that differ from those of other coq genes. We first confirmed that coq7 is necessary for the...
Topics
- Cytochromes c
- Fungal Proteins
- Mutation
- Oxidative Stress
- Phenotype
- Schizosaccharomyces
- Sequence Deletion
- Ubiquinone
