Article
Coenzyme Q plays opposing roles on bacteria/fungi and viruses in Drosophila innate immunity.
International journal of immunogenetics - 1 Aug 2011
Cheng W, Song C, Anjum K M, Chen M, Li D, Zhou H, Wang W, Chen J
Abstract excerpt
Coenzyme Q (CoQ or ubiquinone) is a lipid-soluble component of virtually all types of cell membranes and has been shown to play multiple metabolic functions. Several clinical diseases including encephalomyopathy, cerebellar ataxia and isolated myopathy were shown to be associated with CoQ deficiency. However, the role of CoQ in immunity has not been defined. In the present study, we showed that flies defective in...
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