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Article

Unraveling CYP2E1 haplotypes in alcoholics from Central Brazil: A comparative study with 1000 genomes population.

Environmental toxicology and pharmacology - 1 Sept 2018

Ramos Jheneffer Sonara Aguiar, Felício Leandro Prado, Alves Alessandro Arruda, Lopes Mariana Paiva, Soares Thannya Nascimento, de Melo E Silva Daniela

Abstract excerpt

We evaluated genetic variability of single nucleotide polymorphisms (SNPs) situated in the CYP2E1 gene promoter in alcoholics. We also compared 1000 Genomes Project of CYP2E1 polymorphisms with frequencies of genotypes and haplotypes. Eight variation points were exclusively found in Brazilians. The allelic distributions of the rs3813867, rs2031920 and rs2031921 polymorphisms in the CYP2E1 showed that the wild...

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PMID: 29940492
DOI: 10.1016/j.etap.2018.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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