Article
Single-Nucleotide Polymorphisms Within the Thrombomodulin Gene (THBD) Predict Mortality in Patients With Graft-Versus-Host Disease.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Oct 2014
Rachakonda Sivaramakrishna P, Penack Olaf, Dietrich Sascha, Blau Olga, Blau Igor Wolfgang, Radujkovic Aleksandar, Isermann Berend, Ho Anthony D, Uharek Lutz, Dreger Peter, Kumar Rajiv, Luft Thomas
Abstract excerpt
PURPOSE: Steroid-refractory graft-versus-host disease (GVHD) is a major and often fatal complication after allogeneic stem-cell transplantation (alloSCT). Although the pathophysiology of steroid refractoriness is not fully understood, evidence is accumulating that endothelial cell stress is invol...
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