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Article

Single Nucleotide Polymorphisms in CD40L Predict Endothelial Complications and Mortality After Allogeneic Stem-Cell Transplantation.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Mar 2018

Rachakonda Sivaramakrishna P, Dai Hao, Penack Olaf, Blau Olga, Blau Igor Wolfgang, Radujkovic Aleksandar, Müller-Tidow Carsten, Kumar Rajiv, Dreger Peter, Luft Thomas

Abstract excerpt

Purpose Endothelial vulnerability is a potential risk factor for complications after allogeneic stem-cell transplantation (alloSCT). The CD40/CD40 ligand (CD40L) axis contributes to inflammatory diseases and is upregulated in endothelial cells upon activation, suggesting a role in alloSCT biology. Here, we studied single nucleotide polymorphisms (SNPs) in the CD40L gene in recipients of alloSCT. Patients and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 29369699
DOI: 10.1200/JCO.2017.76.4662

Genes

NRM
THBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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