Article
Mapping MHC haplotype effects in unrelated donor hematopoietic cell transplantation.
Blood - 7 Mar 2013
Petersdorf Effie W, Malkki Mari, Horowitz Mary M, Spellman Stephen R, Haagenson Michael D, Wang Tao
Abstract excerpt
Life-threatening risks associated with HLA-mismatched unrelated donor hematopoietic cell transplantation limit its general application for the treatment of blood diseases. The increased risks might be explained by undetected genetic variation within the highly polymorphic major histocompatibility complex (MHC) region. We retrospectively assessed each of 1108 MHC region single nucleotide polymorphisms (SNPs) in...
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