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Methylation of viral and host genes and severity of cervical lesions associated with human papillomavirus type 16

16 Sept 2014

Abstract excerpt

Methylation of human papillomavirus (HPV) and host genes may predict cervical cancer risk. We examined the methylation status of selected sites in HPV16 and human genes in DNA extracted from exfoliated cervical cell samples of 244 women harboring HPV16-positive cancer or cervical intraepithelial neoplasia (CIN) or negative for intraepithelial lesions or malignancy (NILM). We quantified the methylation of CpG...

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PMID: 25203794
DOI: 10.1002/ijc.29196

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