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Article

Aberrant DNA methylation in cervical carcinogenesis

29 Aug 2012

Abstract excerpt

Persistent infection with high-risk types of human papillomavirus(HPV) is known to cause cervical cancer; however, additional genetic and epigenetic alterations are required for progression from precancerous disease to invasive cancer. DNA methylation is an early and frequent molecular alteration in cervical carcinogenesis. In this review, we summarize DNA methylation within the HPV genome and human genome and...

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Identifiers

PMID: 22943599
DOI: 10.5732/cjc.012.10033

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