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A DNA methylation classifier of cervical precancer based on human papillomavirus and human genes

18 Feb 2014

Abstract excerpt

Testing for high-risk (hr) types of human papillomavirus (HPV) is highly sensitive as a screening test of high-grade cervical intraepithelial neoplastic (CIN2/3) disease, the precursor of cervical cancer. However, it has a relatively low specificity. Our objective was to develop a prediction rule with a higher specificity, using combinations of human and HPV DNA methylation. Exfoliated cervical specimens from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24535756
DOI: 10.1002/ijc.28790

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