Article
Functional polymorphisms in interleukin-23 receptor and susceptibility to coronary artery disease.
DNA and cell biology - 1 Dec 2014
Zhang Meiyan, Cai Zhen-Rong, Zhang Bili, Cai Xinmeng, Li Wei, Guo Zhifu, Ma Lan
Abstract excerpt
As a key element in the T-helper 17 (Th17) cell-mediated inflammatory process, interleukin-23 receptor (IL-23R) may play a crucial role in the pathogenesis of atherosclerosis. Single nucleotide polymorphisms (SNPs) in IL-23R have been studied in several diseases. However, its association with coronary artery disease (CAD) remains unclear. This study examined whether genetic polymorphisms in IL-23R were associated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
