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Article

Functional polymorphisms in interleukin-23 receptor and susceptibility to coronary artery disease.

DNA and cell biology - 1 Dec 2014

Zhang Meiyan, Cai Zhen-Rong, Zhang Bili, Cai Xinmeng, Li Wei, Guo Zhifu, Ma Lan

Abstract excerpt

As a key element in the T-helper 17 (Th17) cell-mediated inflammatory process, interleukin-23 receptor (IL-23R) may play a crucial role in the pathogenesis of atherosclerosis. Single nucleotide polymorphisms (SNPs) in IL-23R have been studied in several diseases. However, its association with coronary artery disease (CAD) remains unclear. This study examined whether genetic polymorphisms in IL-23R were associated...

Topics

Adult
Aged
Case-Control Studies
Coronary Artery Disease
Diabetes Mellitus
Female
Gene Expression
Genetic Predisposition to Disease
Humans
Hypertension
Leukocytes, Mononuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Polymorphism, Single Nucleotide

RNA, Messenger

Receptors, Interleukin

Source

Open in PubMed Open full text

Identifiers

PMID: 25192515
DOI: 10.1089/dna.2014.2573
PMCID: PMC4248252

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-25192515-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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