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Article

Gene polymorphism in IL17A and gene-gene interaction in the IL23R/IL17A axis are associated with susceptibility to coronary artery disease.

Cytokine - 1 Apr 2023

Zhang Hongsong, Nie Shaofang, Chen Qianwen, Wang Pengyun, Xu Chengqi, Tu Xin, Zhang Lifang, Kenneth Wang Qing, Zha Lingfeng

Abstract excerpt

AIMS: Studies have confirmed that the IL-23R/IL-17A axis plays an important role in the development of autoimmune and inflammatory diseases. However, its role in coronary artery disease (CAD) remains unclear. Here, we conducted a large sample case-control study to investigate the association between the IL23R/IL17A axis and CAD in the Chinese Han population. METHODS: Two SNPs, rs2275913: G>A (IL17A) and...

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PMID: 36804259
DOI: 10.1016/j.cyto.2023.156142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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