Gene polymorphism in IL17A and gene-gene interaction in the IL23R/IL17A axis are associated with susceptibility to coronary artery disease.

doi:10.1016/j.cyto.2023.156142

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Article

Gene polymorphism in IL17A and gene-gene interaction in the IL23R/IL17A axis are associated with susceptibility to coronary artery disease.

Cytokine - 1 Apr 2023

Zhang Hongsong, Nie Shaofang, Chen Qianwen, Wang Pengyun, Xu Chengqi, Tu Xin, Zhang Lifang, Kenneth Wang Qing, Zha Lingfeng

Abstract excerpt

AIMS: Studies have confirmed that the IL-23R/IL-17A axis plays an important role in the development of autoimmune and inflammatory diseases. However, its role in coronary artery disease (CAD) remains unclear. Here, we conducted a large sample case-control study to investigate the association betw...

Topics

Humans
Interleukin-17
Coronary Artery Disease
Case-Control Studies
Polymorphism, Single Nucleotide
Cholesterol
Genetic Predisposition to Disease
Receptors, Interleukin

Source

Open in PubMed

Identifiers

PMID: 36804259
DOI: 10.1016/j.cyto.2023.156142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-36804259-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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