Article
Analysis of the association between IL-23R rs11209026 polymorphism and incidence of atherosclerosis.
International journal of immunogenetics - 1 Oct 2015
Kave M, Shadman M, Alizadeh A, Samadi M
Abstract excerpt
Th17/IL-23 axis is an important pro-inflammatory pathway in atherosclerosis. IL-23 receptor (IL-23R) pathway has an important role in T-helper cells 17 (Th17) differentiation and survival. We compared normal subjects and patients with atherosclerosis in terms of the R381Q variant of the IL-23R gene as a functional single-nucleotide polymorphism (SNP). This case-control study recruited 200 patients who presented...
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