Article
Association between interleukin-17A polymorphism and coronary artery disease susceptibility in the Chinese Han population.
Genetics and molecular research : GMR - 12 Aug 2016
Su G B, Guo X L, Liu X C, Cui Q T, Zhou C Y
Abstract excerpt
Coronary artery disease (CAD) is a major global health problem. In China, the incidence of CAD and the rate of mortality arising from it have increased every year. Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by activated T cells, and it may be involved in the development of CAD. Genetic polymorphisms in functional regions of the IL17A gene have a plausible role in modulating the risk of CAD....
Topics
- Aged
- Case-Control Studies
- China
- Coronary Artery Disease
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Interleukin-17