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Article

Polymorphism of IL-12/IL-23 axis is associated with coronary heart disease.

Journal of cellular and molecular medicine - 1 Feb 2024

Dong Jiangtao, Chen Qianwen, Xie Tian, Wang Mengru, Wang Mengqi, Zha Lingfeng

Abstract excerpt

IL12B encodes the shared p40 subunit (IL-12p40) of IL-12 and IL-23, which have diverse immune functions and are closely related to the occurrence and development of atherosclerosis (AS). However, the exact role of IL12B in coronary heart disease (CHD) was still unknown. A case-control association analysis was performed between five single nucleotide polymorphisms (SNPs) of IL12B (rs1003199, rs3212219, rs2569254,...

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 38189641
DOI: 10.1111/jcmm.18100
PMCID: PMC10844691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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