Article
Interleukin-23 receptor gene polymorphisms is associated with dilated cardiomyopathy in Chinese Han population.
Tissue antigens - 1 Apr 2009
Chen Y, Zhou B, Peng Y, Wang Y, Li C, Ding X, He X, Xu J, Huang L, Rao L
Abstract excerpt
Idiopathic dilated cardiomyopathy (DCM) is characterized by ventricular chamber enlargement and systolic dysfunction with normal left ventricular wall thickness. The pathogenesis of DCM has been extensively investigated for many years, but it remains uncertain. Recently, many studies indicated that autoimmune mechanisms are likely to participate in the pathogenesis of DCM. Interleukin-23 receptor (IL-23R) gene...
Topics
- Asian People
- Cardiomyopathy, Dilated
- Case-Control Studies
- China
- Female
- Gene Frequency
- Genotype
- Humans
- Linkage Disequilibrium
- Male
- Middle Aged
- Polymorphism, Genetic
- Population Groups
- Receptors, Interleukin