Article
Absence of the human CYP2C8*3 allele in Ugandan children exposed to Plasmodium falciparum malaria.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2014
Paganotti Giacomo Maria, Cosentino Valentina, Russo Gianluca, Tabacchi Francesca, Gramolelli Silvia, Coluzzi Mario, Romano Rita
Abstract excerpt
Study of host pharmacogenetics can improve our knowledge of mechanisms of drug resistance selection and spread. This issue has recently been addressed with respect to chloroquine and amodiaquine in malaria endemic areas of West and East Africa. Here we report, from surveys performed in two different areas of Uganda, that the human CYP2C8*3 allele, which had been reported to be strongly associated with parasite...
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