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Article

Human genetic variation is associated with Plasmodium falciparum drug resistance.

The Journal of infectious diseases - 1 Dec 2011

Paganotti Giacomo M, Gallo Baba C, Verra Federica, Sirima Bienvenu S, Nebié Issa, Diarra Amidou, Coluzzi Mario, Modiano David

Abstract excerpt

One approach to investigate if human genetic variation influences the selection of Plasmodium falciparum drug resistance is to compare the frequency of resistant infections among human populations differing in their genetic background and living in the same epidemiological context. A further complementary approach consists in comparing drug resistance among subjects differing for genes involved in drug...

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PMID: 21998472
DOI: 10.1093/infdis/jir629

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