Hepatitis C virus genetic variability and evolution

doi:10.4254/wjh.v7.i6.831

Article

Hepatitis C virus genetic variability and evolution

1 Jan 2015

Abstract excerpt

Hepatitis C virus (HCV) has infected over 170 million people worldwide and creates a huge disease burden due to chronic, progressive liver disease. HCV is a single-stranded, positive sense, RNA virus, member of the Flaviviridae family. The high error rate of RNA-dependent RNA polymerase and the pressure exerted by the host immune system, has driven the evolution of HCV into 7 different genotypes and more than 67...

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