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Article

Plasmid copy number underlies adaptive mutability in bacteria.

Genetics - 1 Nov 2014

Sano Emiko, Maisnier-Patin Sophie, Aboubechara John Paul, Quiñones-Soto Semarhy, Roth John R

Abstract excerpt

The origin of mutations under selection has been intensively studied using the Cairns-Foster system, in which cells of an Escherichia coli lac mutant are plated on lactose and give rise to 100 Lac+ revertants over several days. These revertants have been attributed variously to stress-induced mutagenesis of nongrowing cells or to selective improvement of preexisting weakly Lac+ cells with no mutagenesis. Most...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25173846
DOI: 10.1534/genetics.114.170068
PMCID: PMC4224180

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Source receipt: pubmed, retrieved 7 Sept 2026.

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