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Article

Transposon stability and a role for conjugational transfer in adaptive mutability.

Proceedings of the National Academy of Sciences of the United States of America - 20 Jun 2000

Godoy V G, Fox M S

Abstract excerpt

Lac(+) revertants of Escherichia coli that occur after prolonged nonlethal selection display a high frequency of transposon loss when the transposon Tn10 and the reverting lacI33 allele are linked on an F'128 episome. As many as 20% of the Lac(+) revertants are sensitive to tetracycline, about half because of transposon loss, nearly all by precise excision, and the remainder because of amplification of both the...

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Identifiers

PMID: 10840058
DOI: 10.1073/pnas.130186597
PMCID: PMC16556

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