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Article

The biology of Lubricin: Near frictionless joint motion

27 Aug 2014

Abstract excerpt

Lubricin is a surface-active mucinous glycoprotein secreted in the synovial joint that plays an important role in cartilage integrity. In healthy joints, lubricin molecules coat the cartilage surface, providing boundary lubrication and preventing cell and protein adhesion. Arthropathy occurring in patients with joint trauma, inflammatory arthritis or genetically mediated lubricin deficiencies have insufficient...

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Identifiers

PMID: 25172828
DOI: 10.1016/j.matbio.2014.08.008

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