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Article

Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal tissues.

BMC genomics - 5 Jun 2017

Zhang Bo, Madden Pamela, Gu Junchen, Xing Xiaoyun, Sankar Savita, Flynn Jennifer, Kroll Kristen, Wang Ting

Abstract excerpt

BACKGROUND: Nicotinic acetylcholine receptors (nAChRs) play an important role in cellular physiology and human nicotine dependence, and are closely associated with many human diseases including cancer. For example, previous studies suggest that nAChRs can re-wire gene regulatory networks in lung cancer cell lines. However, the tissue specificity of nAChRs genes and their regulation remain unexplored. RESULT: In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28583088
DOI: 10.1186/s12864-017-3813-4
PMCID: PMC5460472

Genes

CHRNA4
CHRNA3
CHRNA5
CHRNB4
FMO3
RXRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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