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Article

NPTX1 is a novel epigenetic regulation gene and associated with prognosis in lung cancer.

Biochemical and biophysical research communications - 6 Mar 2015

Zhou Chengzhi, Qin Yinyin, Xie Zhanhong, Zhang Jiexia, Yang Mingou, Li Shiyue, Chen Rongchang

Abstract excerpt

BACKGROUND: CpG island hypermethylation of gene promoters is a well-known mechanism of epigenetic regulation of tumor related-genes and is directly linked to lung carcinogenesis. Alterations in the pattern of methylation of the NPTX1 gene have not yet been studied in detail in human lung cancer. METHODS: Methylation-specific PCR (MSP) and bisulfite sequencing PCR (BSP) were used to analyze promoter methylation...

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Identifiers

PMID: 25646694
DOI: 10.1016/j.bbrc.2015.01.124

Genes

NPTX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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